Rabies is a preventable viral disease of mammals most often transmitted through the bite of a rabid animal. The vast majority of rabies cases reported to the Centers for Disease Control and Prevention (CDC) each year occur in wild animals like raccoons, skunks, bats, and foxes.
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Rabies remains a problem in most countries of Southeast Asia, where stray dogs and cats are common. Financial, political, and cultural issues are the main barriers to public health authorities’ controlling the disease in animals.1 Local people and travelers in this area are inevitably at risk of exposure to the rabies virus if bitten or licked by an infected animal. Pre-exposure prophylaxis is an excellent preventive measure against rabies in travelers. However, it is expensive, and the cost-benefit relationship is not clear, so that it has limited application in general travel-medicine practice.